Modification of tryptophan transport system and its impact on production of L-tryptophan in Escherichia coli.

@article{Liu2012ModificationOT,
  title={Modification of tryptophan transport system and its impact on production of L-tryptophan in Escherichia coli.},
  author={Qian Liu and Yongsong Cheng and Xixian Xie and Qingyang Xu and Ning Chen},
  journal={Bioresource technology},
  year={2012},
  volume={114},
  pages={549-54}
}
The production of L-tryptophan through chemical synthesis, direct fermentation, bioconversion and enzymatic conversion has been reported. However, the role of transport system for aromatic amino acids in L-tryptophan producing strains has not been fully explored. In this study, the fact was revealed that L-tryptophan production and cell growth were affected by the modification of transport systems based on YddG functioning as aromatic amino acid excretion and AroP functioning as general… CONTINUE READING
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