Modification of tight junction function by protein kinase C isoforms.

  title={Modification of tight junction function by protein kinase C isoforms.},
  author={Hector Clarke and Cristina Marano and Alejandro Peralta Soler and James M Mullin},
  journal={Advanced drug delivery reviews},
  volume={41 3},
The regulation of tight junction permeability by a variety of signal transduction pathways is summarized. An emphasis is placed on regulation of paracellular permeability by the protein kinase C family of isoforms, which involves the reporting of a large number of studies using the phorbol ester family of protein kinase C activators. The ability of protein kinase C activation to open epithelial barriers to a very wide range of solutes is emphasized, but then countered with discussion of the… CONTINUE READING

From This Paper

Figures, tables, results, connections, and topics extracted from this paper.
27 Extracted Citations
0 Extracted References
Similar Papers

Citing Papers

Publications influenced by this paper.
Showing 1-10 of 27 extracted citations

Similar Papers

Loading similar papers…