Modification of the haemodynamic responses to induction of anaesthesia and tracheal intubation with alfentanil, esmolol and their combination.

@article{Korpinen1995ModificationOT,
  title={Modification of the haemodynamic responses to induction of anaesthesia and tracheal intubation with alfentanil, esmolol and their combination.},
  author={R Korpinen and Laila Saarnivaara and Karen Siren and Seppo S Sarna},
  journal={Canadian journal of anaesthesia = Journal canadien d'anesthesie},
  year={1995},
  volume={42 4},
  pages={298-304}
}
The purpose of this double-blind randomized work was to study the effect of alfentanil and esmolol and their half-dose combination on the increases of heart rate and arterial pressure and on the prolongation of the QTc interval of the ECG occurring during anaesthetic induction. Sixty ASA class I-II patient with mean age ranging from 26 to 32 yr among the groups. Patients were allocated to one of four equal groups to receive saline, esmolol 2 mg.kg-1, alfentanil 0.03 mg.kg-1 and alfentanil 0.015… CONTINUE READING