Modification of the association between recreational physical activity and survival after breast cancer by promoter methylation in breast cancer-related genes

Abstract

Mechanisms underlying the inverse association between physical activity and survival after breast cancer are unresolved, but DNA methylation may play a role. We hypothesized that promoter methylation of breast cancer-related genes, as well as global methylation, may modify the association between prediagnostic recreational physical activity (RPA) and breast… (More)
DOI: 10.1186/s13058-017-0811-z

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