Modification of rapid human immunodeficiency virus (HIV) antibody assay protocols for detecting recent HIV seroconversion.

@article{Soroka2005ModificationOR,
  title={Modification of rapid human immunodeficiency virus (HIV) antibody assay protocols for detecting recent HIV seroconversion.},
  author={Stephen D Soroka and Timothy C. Granade and D. Candal and Bharat S. Parekh},
  journal={Clinical and diagnostic laboratory immunology},
  year={2005},
  volume={12 8},
  pages={
          918-21
        }
}
Assay protocols of three rapid human immunodeficiency virus (HIV) assays, OraQuick-1/2, SeroStrip-1/2, and Determine-1/2, were modified to detect recent HIV seroconversion using a higher dilution of serum specimens. Optimal predilution of specimens resulted in negative test results during early periods of seroconversion (about 6 months), when antibody levels were low. A total of 269 seropositive specimens from routine HIV type 1 testing and from commercial sources (low-titer and seroconversion… CONTINUE READING

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