Modification of polyurethaneurea with PEG and YIGSR peptide to enhance endothelialization without platelet adhesion.

@article{Jun2005ModificationOP,
  title={Modification of polyurethaneurea with PEG and YIGSR peptide to enhance endothelialization without platelet adhesion.},
  author={Ho-wook Jun and Jennifer L West},
  journal={Journal of biomedical materials research. Part B, Applied biomaterials},
  year={2005},
  volume={72 1},
  pages={131-9}
}
Improved endothelialization without platelet adhesion is essential to enhance the long-term patency of synthetic vascular grafts and other blood-contacting devices. We have developed a dually modified polyurethaneurea by incorporating endothelial cell adhesive YIGSR peptide sequences as chain extenders and nonthrombogenic PEG as a soft segment (PUUYIGSR-PEG… CONTINUE READING