Modification of phospholipid metabolism in human red cells by primaquine. A possible mechanism in drug-induced hemolysis.

@article{Wittels1970ModificationOP,
  title={Modification of phospholipid metabolism in human red cells by primaquine. A possible mechanism in drug-induced hemolysis.},
  author={Benjamin Wittels},
  journal={Biochimica et biophysica acta},
  year={1970},
  volume={210 1},
  pages={
          74-85
        }
}
  • B. Wittels
  • Published 9 June 1970
  • Biology, Chemistry
  • Biochimica et biophysica acta
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16 Citations
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16 Citations

In vitro inhibition of lipolysis by pyrimethamine in blood from ducks parasitized with Plasmodium lophurae.
TLDR
It appeared that pyrimethamine induced an increase in the excretion of labeled phospholipid, triglyceride, sterol, and sterol ester into the plasma, whereas there was a decrease in the level of labeled free fatty acid.
Effects of L-carnitine and its acetate and propionate esters on the molecular dynamics of human erythrocyte membrane.
Primaquine Diphosphate: Inhibition of Newcastle Disease Virus Replication
TLDR
It is suggested that the major role of primaquine is inhibition of protein synthesis; this results in changes in: hemadsorption, redistribution of lectin receptors, release of progeny, and virus-induced RNA synthesis.
Incorporation of Fatty Acids and Amino Acids by Cultured Pneumocystis carinii
TLDR
The formation of radioactive P.cariniiā€specific proteins indicated that the cultured organisms carried out transcription and translation and that the incorporation of amino acids was dependent upon P. carinii rather than rare human embryonic lung cells.
Lysophosphatidylcholine-induced lysis of erythrocytes in Duchenne and myotonic dystrophies and in Huntington's disease
Changes in fatty acid metabolism after erythrocyte peroxidation: stimulation of a membrane repair process.
TLDR
The net effect of these events represents the operation of repair processes which distort the usual fatty acid composition of erythrocyte membranes in the presence of H(2)O(2).
Selective solubilization of proteins from red blood cell membranes by protein perturbants.
  • T. SteckJ. Yu
  • Biology, Chemistry
    Journal of supramolecular structure
  • 1973
TLDR
The distinctive elution behavior which defines these two groups of polypeptides relates both to their chemical composition and their organizational disposition in the membrane.
Enzymes of Membrane Phospholipid Metabolism in Animals
TLDR
This chapter is designed to help the readers understand the multiple variables that influence the current understanding of the control of membrane phospholipids.
Lipid exchange and transfer between biological lipid-protein structures.
  • F. Bell
  • Chemistry, Biology
    Progress in lipid research
  • 1978
Structural changes in alkaline-treated postsynaptic membranes from Torpedo marmorata are not due to lipid hydrolysis.
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TLDR
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SUMMARY Thin-layer chromatography of phospholipids and cerebrosides was performed on Silica Gel G plates using a mixture of chloroform-methanol-acetic acid-water as development solvent. Two types ofā€¦
Synthesen von Cholinphosphatiden, V. Palmitoylā€propandiolā€(1.3)ā€phosphorylcholin (2ā€Desoxylysolecithin) und Ļ‰.Ļ‰ā€²ā€Alkandiolā€Analoga
Die Phosphorsaurecholinester 2 einiger Palmitoyl-Ļ‰.Ļ‰ā€²-alkandiole (1) ā€“ im einfachsten Falle von Palmitoyl-propandiol-(1.3) ā€“ wurden dargestellt.
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