Modification of iron regulation by the inflammatory response.

@article{Weiss2005ModificationOI,
  title={Modification of iron regulation by the inflammatory response.},
  author={Guenter Weiss},
  journal={Best practice & research. Clinical haematology},
  year={2005},
  volume={18 2},
  pages={
          183-201
        }
}
Iron is an essential compound for immunosurveillance because of its growth-promoting and differentiation-inducing properties for immune cells and its interference with cell-mediated immune effector pathways and cytokine activities. Thus, the reticuloendothelial system has generated sophisticated strategies to control iron metabolism in general and the handling of the metal within immune cells. Cytokines, immune-cell-derived radicals, and acute-phase proteins affect the regulation of iron… CONTINUE READING

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