Modification of gene expression induced in human osteogenic and osteosarcoma cells by culture on a biphasic calcium phosphate bone substitute.

@article{Rochet2003ModificationOG,
  title={Modification of gene expression induced in human osteogenic and osteosarcoma cells by culture on a biphasic calcium phosphate bone substitute.},
  author={Nathalie Rochet and Agn{\`e}s Loubat and J Laugier and P. Hofman and J M Bouler and Guy Daculsi and G. F. Carle and Bernard Rossi},
  journal={Bone},
  year={2003},
  volume={32 6},
  pages={602-10}
}
Bone hybrids made of bioceramics seeded with mesenchymal or osteoblastic cells are very promising alternatives to autologous bone graft. Along this line, the development of in vitro models, dedicated to analyze the influence of these biomaterials on osteogenic cells, will help to improve the performance of these bone substitutes. In the present work we analyzed the effects of a macroporous biphasic calcium phosphate ceramic (BCP, Triosite) on three different human osteosarcoma cell lines and on… CONTINUE READING
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