Modification of cocaine‐induced behavioral and neurochemical effects by serotonin1A receptor agonist/antagonist in mice

@article{Nakamura2006ModificationOC,
  title={Modification of cocaine‐induced behavioral and neurochemical effects by serotonin1A receptor agonist/antagonist in mice},
  author={Shigeo Nakamura and Yukio Ago and Aiko Hayashi and Soichi Itoh and Michiya Kakuda and Hitoshi Hashimoto and Akemichi Baba and Toshio Matsuda},
  journal={Synapse},
  year={2006},
  volume={60}
}
Administration of cocaine causes a locomotor stimulant effect and increases extracellular levels of serotonin (5‐HT) and dopamine (DA) in the brains of rodents. Previous studies show that 5‐HT1A receptor agonist and antagonist modify the cocaine‐induced behavioral and neurochemical effects in the rats. However, the role of the 5‐HT system on the effects of cocaine has not been studied in the prefrontal cortex. The present study examined in ddY‐strain male mice the effects of the 5‐HT1A receptor… Expand
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