Modification of cocaine‐induced behavioral and neurochemical effects by serotonin1A receptor agonist/antagonist in mice

@article{Nakamura2006ModificationOC,
  title={Modification of cocaine‐induced behavioral and neurochemical effects by serotonin1A receptor agonist/antagonist in mice},
  author={Shigeo Nakamura and Y. Ago and A. Hayashi and S. Itoh and Michiya Kakuda and H. Hashimoto and A. Baba and T. Matsuda},
  journal={Synapse},
  year={2006},
  volume={60}
}
Administration of cocaine causes a locomotor stimulant effect and increases extracellular levels of serotonin (5‐HT) and dopamine (DA) in the brains of rodents. Previous studies show that 5‐HT1A receptor agonist and antagonist modify the cocaine‐induced behavioral and neurochemical effects in the rats. However, the role of the 5‐HT system on the effects of cocaine has not been studied in the prefrontal cortex. The present study examined in ddY‐strain male mice the effects of the 5‐HT1A receptor… Expand
Serotonin and psychostimulant addiction: Focus on 5-HT1A-receptors
The role of serotonin in drug use and addiction
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