Modification of cholesterool crystal-induced inflammation

  title={Modification of cholesterool crystal-induced inflammation},
  author={Charles W. Denko and Mark Petricevic},
  journal={Agents and Actions},
Cholesterol crystals induced inflammation in normal rats upon being injected into the footpad. Cholesterol caused less swelling than did an equal amount (3 mg) of monosodium urate crystals. In rats made deficient in essential fatty acids on the basis of clinical criteria (thereby presumably being deficient in prostaglandins) cholesterol crystals did not… CONTINUE READING