Modification of chemotherapeutic effects on L1210 cells using hematoporphyrin and light.

Abstract

Tissue culture experiments were done to evaluate the possibility of modifying the response curves of phenylalanine mustard (LPAM) and actinomycin D on L1210 cells, using moderately toxic levels of photodynamic injury provided by light and hematoporphyrin (HP). Cells were grown and treated in Roswell Park Memorial Institute Medium 1630 containing 20% horse… (More)

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