Modification of age-related immune decline in mice dietarily restricted from or after midadulthood.

Abstract

Although weaning-initiated dietary restriction of rodents is known to increase maximum survivorship and inhibit spontaneous late-life disease and immunologic aging, restriction begun in adulthood has been much less thoroughly evaluated. In the present studies, male mice of a long-lived F1 hybrid strain were gradually restricted dietarily beginning at 12 mo… (More)

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@article{Weindruch1982ModificationOA, title={Modification of age-related immune decline in mice dietarily restricted from or after midadulthood.}, author={R. H. Weindruch and Susan Gottesman and Roy L. Walford}, journal={Proceedings of the National Academy of Sciences of the United States of America}, year={1982}, volume={79 3}, pages={898-902} }