Modification of a ubiquitin-like protein Paz2 conducted micropexophagy through formation of a novel membrane structure.

@article{Mukaiyama2004ModificationOA,
  title={Modification of a ubiquitin-like protein Paz2 conducted micropexophagy through formation of a novel membrane structure.},
  author={Hiroyuki Mukaiyama and Misuzu Baba and Masako Osumi and Satoshi Aoyagi and Nobuo Kato and Yoshinori Ohsumi and Yasuyoshi Sakai},
  journal={Molecular biology of the cell},
  year={2004},
  volume={15 1},
  pages={
          58-70
        }
}
Microautophagy is a versatile process in which vacuolar or lysosomal membranes directly sequester cytosolic targets for degradation. Recent genetic evidence suggested that microautophagy uses molecular machineries essential for macroautophagy, but the details of this process are still unknown. In this study, a ubiquitin-like protein Paz2 essential for micropexophagy in the yeast Pichia pastoris has been shown to receive modification through the function of Paz8 and Gsa7, yielding a modified… CONTINUE READING