Modification and Validation of the Triglyceride-to-HDL Cholesterol Ratio as a Surrogate of Insulin Sensitivity in White Juveniles and Adults without Diabetes Mellitus: The Single Point Insulin Sensitivity Estimator (SPISE).

@article{Paulmichl2016ModificationAV,
  title={Modification and Validation of the Triglyceride-to-HDL Cholesterol Ratio as a Surrogate of Insulin Sensitivity in White Juveniles and Adults without Diabetes Mellitus: The Single Point Insulin Sensitivity Estimator (SPISE).},
  author={Katharina Paulmichl and Mensud Hatunic and Kurt H{\o}jlund and Aleksandra Jotic and Michael Krebs and Asimina Mitrakou and Francesca Porcellati and Andrea Tura and Peter Bergsten and Anders Forslund and Hannes Manell and Kurt Widhalm and Daniel Weghuber and Christian-Heinz Anderwald},
  journal={Clinical chemistry},
  year={2016},
  volume={62 9},
  pages={
          1211-9
        }
}
BACKGROUND The triglyceride-to-HDL cholesterol (TG/HDL-C) ratio was introduced as a tool to estimate insulin resistance, because circulating lipid measurements are available in routine settings. Insulin, C-peptide, and free fatty acids are components of other insulin-sensitivity indices but their measurement is expensive. Easier and more affordable tools are of interest for both pediatric and adult patients. METHODS Study participants from the Relationship Between Insulin Sensitivity and… CONTINUE READING
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