Modic changes: a systematic review of the literature

  title={Modic changes: a systematic review of the literature},
  author={Yue-hui Zhang and Chang-Qing Zhao and Lei-sheng Jiang and Xiao-Dong Chen and Li-yang Dai},
  journal={European Spine Journal},
Modic changes (MC) are a common phenomenon on magnetic resonance imaging (MRI) in spinal degenerative diseases and strongly linked with low back pain (LBP). Histology, radiology, potential mechanisms, natural history and clinical studies of MC has formed the foundation on which our understanding of spinal degenerative diseases is built. The objective of this study was to provide a review of recent important advances in the study of MC and their clinical significance. This review article… CONTINUE READING
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