Modest weight gain is associated with sympathetic neural activation in nonobese humans.

@article{Gentile2007ModestWG,
  title={Modest weight gain is associated with sympathetic neural activation in nonobese humans.},
  author={Christopher L Gentile and Jeb S. Orr and Brenda M Davy and Kevin P. Davy},
  journal={American journal of physiology. Regulatory, integrative and comparative physiology},
  year={2007},
  volume={292 5},
  pages={R1834-8}
}
We tested the hypothesis that modest, overfeeding-induced weight gain would increase sympathetic neural activity in nonobese humans. Twelve healthy males (23 +/- 2 years; body mass index, 23.8 +/- 0.7) were overfed approximately 1,000 kcal/day until a 5-kg weight gain was achieved. Muscle sympathetic nerve activity (MSNA, microneurography), blood pressure, body composition (dual energy X-ray absorptiometry), and abdominal fat distribution (computed tomography) were measured at baseline and… CONTINUE READING

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