Modest Waning of Influenza Vaccine Efficacy and Antibody Titers During the 2007-2008 Influenza Season.

@article{Petrie2016ModestWO,
  title={Modest Waning of Influenza Vaccine Efficacy and Antibody Titers During the 2007-2008 Influenza Season.},
  author={Joshua G Petrie and Suzanne E. Ohmit and Rachel K Truscon and Emileigh Johnson and Thomas M Braun and Min Z. Levine and Maryna C Eichelberger and Arnold S. Monto},
  journal={The Journal of infectious diseases},
  year={2016},
  volume={214 8},
  pages={
          1142-9
        }
}
BACKGROUND Antibody titers decrease with time following influenza vaccination, raising concerns that vaccine efficacy might wane. However, the relationship between time since vaccination and protection is unclear. METHODS Time-varying vaccine efficacy (VE[t]) was examined in healthy adult participants (age range, 18-49 years) in a placebo-controlled trial of inactivated influenza vaccine (IIV) and live-attenuated influenza vaccine (LAIV) performed during the 2007-2008 influenza season… CONTINUE READING
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