Modes of antifungal action of (2E)-alkenals against Saccharomyces cerevisiae.

@article{Kubo2003ModesOA,
  title={Modes of antifungal action of (2E)-alkenals against Saccharomyces cerevisiae.},
  author={Isao Kubo and Ken-Ichi Fujita and Aya Kubo and Ken-ichi Nihei and Christopher S. Lunde},
  journal={Journal of agricultural and food chemistry},
  year={2003},
  volume={51 14},
  pages={3951-7}
}
A series of aliphatic (2E)-alkenals from C(5) to C(14) were tested for their antifungal activity against Saccharomyces cerevisiae ATCC 7754. (2E)-Undecenal (C(11)) was found to be the most effective with the minimum fungicidal concentration (MFC) of 6.25 microgram/mL, followed by (2E)-decenal (C(10)) with an MFC of 12.5 microgram/mL. The time-kill curve study showed that (2E)-undecenal was fungicidal against S. cerevisiae at any growth stage, and this activity was not influenced by pH values… CONTINUE READING