Modern thoughts on an ancyent marinere: function, evolution, regulation.

  title={Modern thoughts on an ancyent marinere: function, evolution, regulation.},
  author={Daniel L. Hartl and Allan R. Lohe and Elena R. Lozovskaya},
  journal={Annual review of genetics},
The mariner/Tc1 superfamily of transposable elements is one of the most diverse and widespread Class II transposable elements. Within the larger assemblage, the mariner-like elements (MLEs) and the Tc1-like elements (TLEs) are distinct families differing characteristically in the composition of the "D,D(35)E" cation-binding domain. Based on levels of sequence similarity, the elements in each family can be subdivided further into several smaller subfamilies. MLEs and TLEs both have an… CONTINUE READING


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