Modern management of myelofibrosis

@article{Cervantes2005ModernMO,
  title={Modern management of myelofibrosis},
  author={F. Cervantes},
  journal={British Journal of Haematology},
  year={2005},
  volume={128}
}
  • F. Cervantes
  • Published 2005
  • Medicine
  • British Journal of Haematology
The conventional treatment of myelofibrosis involves a wait‐and‐see approach for asymptomatic patients, oral chemotherapy for the hyperproliferative forms of the disease, androgens or erythropoietin for the anaemia, and splenectomy in selected patients. Low‐dose thalidomide plus prednisone is a well‐tolerated therapy for the anaemia and the thrombocytopenia of myelofibrosis, whereas imatinib has shown little efficacy. Allogeneic stem cell transplantation (allo‐SCT) is the only curative therapy… Expand
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