Modern evolution of a single-copy gene: the immunoglobulin C kappa locus in wild mice.

@article{JouvinMarche1988ModernEO,
  title={Modern evolution of a single-copy gene: the immunoglobulin C kappa locus in wild mice.},
  author={Evelyne Jouvin-Marche and Andrew R. Cuddihy and Sandra Butler and J. Norman Hansen and W. M. Fitch and Stuart Rudikoff},
  journal={Molecular biology and evolution},
  year={1988},
  volume={5 5},
  pages={500-11}
}
The immunoglobulin kappa light-chain constant region gene (C kappa) has been cloned and sequenced from five wild mouse species. Analysis of these data has permitted an assessment of single-copy gene evolution during a limited time period as defined by the genus Mus. Sequence conservation was found to be as high (or higher) in the 5' and enhancer regions as… CONTINUE READING