• Corpus ID: 49222886

Modern Management of Deep Venous Thrombosis

@inproceedings{Sharifi2014ModernMO,
  title={Modern Management of Deep Venous Thrombosis},
  author={Mohsen Sharifi and Vein Clinic},
  year={2014}
}

• M. Sharifi, Vein Clinic
• Published 2014
• Medicine

Deep venous thrombosis (DVT) is a common and underdiagnosed disease spectrum with a high mor- tality and morbidity. For over 50 years it has been treated with different forms of heparin and vitamin K antagonists (VKA). It is not merely an acute event but the beginning of a chronic disease process that could continue for the rest of a patient's life. Over the last 5 years new oral anticoagulants have been introduced that can replace VKA in the majority of patients. Additionally there are now emerging data from randomized trials on the superiority of percutaneous endovenous intervention (PEVI) over conventional treatment in the reduction of post-thrombotic syndrome and recurrent venous thromboembolism (VTE). This paper reviews the important literature and dis- cusses the author's approach, which is a combination of new oral anticoagulants in conjunction with PEVI and the utilization of the concept of "safe dose" thrombolysis in the treatment of VTE.