Moderate-to-High Intensity Physical Exercise in Patients with Alzheimer's Disease: A Randomized Controlled Trial.

@article{Hoffmann2015ModeratetoHighIP,
  title={Moderate-to-High Intensity Physical Exercise in Patients with Alzheimer's Disease: A Randomized Controlled Trial.},
  author={Kristine Hoffmann and Nanna Aue Sobol and Kristian Steen Frederiksen and Nina Beyer and Asmus Vogel and Karsten Vestergaard and Hans Br{\ae}ndgaard and Hanne Gottrup and Annette Lolk and Lene Wermuth and Soren Dyring Jacobsen and Lars P Laugesen and Robert G Gergelyffy and Peter H{\o}gh and Eva Bjerregaard and Birgitte Bo Andersen and Volkert D Siersma and Peter Johannsen and Carl Cotman and Gunhild Waldemar and Steen Gregers Hasselbalch},
  journal={Journal of Alzheimer's disease : JAD},
  year={2015},
  volume={50 2},
  pages={
          443-53
        }
}
BACKGROUND Studies of physical exercise in patients with Alzheimer's disease (AD) are few and results have been inconsistent. OBJECTIVE To assess the effects of a moderate-to-high intensity aerobic exercise program in patients with mild AD. METHODS In a randomized controlled trial, we recruited 200 patients with mild AD to a supervised exercise group (60-min sessions three times a week for 16 weeks) or to a control group. Primary outcome was changed from baseline in cognitive performance… CONTINUE READING

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References

Publications referenced by this paper.
SHOWING 1-10 OF 45 REFERENCES

Symbol Digit Modalities Test

VIEW 8 EXCERPTS
HIGHLY INFLUENTIAL

Effect of a 24-month physical activity intervention vs health education on cognitive outcomes in sedentary older adults: The LIFE randomized trial

K. Hoffmann
  • Study LIFE,
  • 2015
VIEW 2 EXCERPTS

Antidepressants for depression in patients with dementia: a review of the literature.

  • The Consultant pharmacist : the journal of the American Society of Consultant Pharmacists
  • 2014
VIEW 1 EXCERPT