Moderate exercise is an antioxidant: upregulation of antioxidant genes by training.

  title={Moderate exercise is an antioxidant: upregulation of antioxidant genes by training.},
  author={Mari-Carmen G{\'o}mez-Cabrera and Elena B. Dom{\`e}nech and J. Vi{\~n}a},
  journal={Free radical biology & medicine},
  volume={44 2},
Exercise causes oxidative stress only when exhaustive. Strenuous exercise causes oxidation of glutathione, release of cytosolic enzymes, and other signs of cell damage. However, there is increasing evidence that reactive oxygen species (ROS) not only are toxic but also play an important role in cell signaling and in the regulation of gene expression. Xanthine oxidase is involved in the generation of superoxide associated with exhaustive exercise. Allopurinol (an inhibitor of this enzyme… CONTINUE READING
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