Moderate excitation leads to weakening of perceptual representations.

@article{Newman2010ModerateEL,
  title={Moderate excitation leads to weakening of perceptual representations.},
  author={Ehren L. Newman and Kenneth A. Norman},
  journal={Cerebral cortex},
  year={2010},
  volume={20 11},
  pages={2760-70}
}
A fundamental goal of memory research is to specify the conditions that lead to the strengthening and weakening of neural representations. Several computational models of memory formation predict that learning effects should vary as a nonmonotonic function of the amount of excitation received by a neural representation. Specifically, moderate excitation should result in synaptic weakening, while strong excitation should result in synaptic strengthening. In vitro investigations of plasticity in… CONTINUE READING
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