Moderate controlled cortical contusion in pigs: effects on multi-parametric neuromonitoring and clinical relevance.

@article{Alessandri2003ModerateCC,
  title={Moderate controlled cortical contusion in pigs: effects on multi-parametric neuromonitoring and clinical relevance.},
  author={Beat Alessandri and Axel Heimann and Ronald Filippi and Laszlo Kopacz and Oliver S. Kempski},
  journal={Journal of neurotrauma},
  year={2003},
  volume={20 12},
  pages={1293-305}
}
Over the last decade, routine neuromonitoring of ICP and CPP has been extended with new on-line techniques such as microdialysis, tissue oxygen (ptiO(2)), acid-base balance (ptiCO(2), pH) and CBF measurements, which so far have not lead to clear-cut therapy approaches in the neurointensive care unit. This is partially due to the complex pathophysiology following a wide-range of brain injuries, and the lack of suitable animal models allowing simultaneous, clinically relevant neuromonitoring… CONTINUE READING