Moderate and prolonged hypercapnic acidosis may protect against ventilator-induced diaphragmatic dysfunction in healthy piglet: an in vivo study

@inproceedings{Jung2013ModerateAP,
  title={Moderate and prolonged hypercapnic acidosis may protect against ventilator-induced diaphragmatic dysfunction in healthy piglet: an in vivo study},
  author={Boris Jung and Mustapha Sebbane and Charlotte Le Goff and Nans Rossel and G{\'e}rald Chanques and Emmanuel Futier and Jean Michel Constantin and Stefan Matecki and Samir Jaber},
  booktitle={Critical care},
  year={2013}
}
INTRODUCTION Protective ventilation by using limited airway pressures and ventilation may result in moderate and prolonged hypercapnic acidosis, as often observed in critically ill patients. Because allowing moderate and prolonged hypercapnia may be considered protective measure for the lungs, we hypothesized that moderate and prolonged hypercapnic acidosis may protect the diaphragm against ventilator-induced diaphragmatic dysfunction (VIDD). The aim of our study was to evaluate the effects of… CONTINUE READING
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