Moderate alcohol use and reduced mortality risk: Systematic error in prospective studies

@article{Fillmore2006ModerateAU,
  title={Moderate alcohol use and reduced mortality risk: Systematic error in prospective studies},
  author={Kaye Middleton Fillmore and William C. Kerr and Tim R Stockwell and Tanya N Chikritzhs and Alan G Bostrom},
  journal={Addiction Research \& Theory},
  year={2006},
  volume={14},
  pages={101 - 132}
}
The majority of prospective studies on alcohol use and mortality risk indicates that abstainers are at increased risk of mortality from both all causes and coronary heart disease (CHD). This meta-analysis of 54 published studies tested the extent to which a systematic misclassification error was committed by including as ‘abstainers’ many people who had reduced or stopped drinking, a phenomenon associated with ageing and ill health. The studies judged to be error free found no significant all… Expand
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References

SHOWING 1-10 OF 123 REFERENCES
Alcohol consumption and mortality in an American male population: recovering the U-shaped curve--findings from the normative Aging Study.
TLDR
Results lend support to the hypothesis of the beneficial effect of moderate drinking, with respect to mortality, as moderate or regular drinkers had lower overall and CHD mortality than lifetime abstainers. Expand
Moderate alcohol and decreased cardiovascular mortality in an elderly cohort.
The data from case control and cohort studies are generally consistent with the hypothesis that moderate alcohol consumption has an inverse relationship with coronary heart disease (CHD).‘.’ However,Expand
Alcohol consumption: protection against coronary heart disease and risks to health.
TLDR
The overall morbidity and mortality experience in this community indicated a protective effect of alcohol against CHD, but adverse health consequences from multiple causes in drinkers who were alcohol dependent. Expand
Changes in Alcohol Intake and Mortality: A Longitudinal Population-based Study
TLDR
Person with stable patterns of light and moderate alcohol intake had the lowest all-cause mortality, consistent with the mortality observed among those who reported stable drinking. Expand
Alcohol and mortality. Results from the EPOZ (Epidemiologic Study of Cardiovascular Risk Indicators) follow-up study.
TLDR
A J- or U-shaped relation between alcohol consumption and CVD mortality could not be confirmed in data but the available information on the amount of alcohol consumed was limited, however, mortality tended to be higher for those who consumed more alcohol. Expand
Light-to-moderate alcohol consumption and mortality in the Physicians' Health Study enrollment cohort.
TLDR
Data support a U-shaped relation between alcohol and total mortality among light-to-moderate drinking men, which may reflect an inverse association for CVD mortality, no association for common site-specific cancers and a possible positive association for less common cancers. Expand
Alcohol Intake, Body Weight, and Mortality in a Multiethnic Prospective Cohort
TLDR
It is found that persons with moderate alcohol intake appear to have a lower risk of dying than nondrinkers, but the possible protective levels of alcohol for women and Asian men appear to be lower than for Caucasian men. Expand
Alcohol and mortality Results from the EPOZ follow-up study
To investigate the association of alcohol intake with mortality from all causes, cardiovascular disease (CVD), cancer and other causes (e.g., accidents, violence, suicide), we performed an analysisExpand
Alcohol consumption and mortality. II. Studies of male populations.
TLDR
It is found that frequent drinking was related to mortality risk, whereas heavier quantity was unrelated, is inconsistent with the belief that daily consumption of a few glasses of wine has salutary effects. Expand
Prospective study of alcohol consumption and risk of coronary disease in men
TLDR
The hypothesis that the inverse relation between alcohol consumption and risk of coronary disease is causal is supported. Expand
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