Moderate alcohol consumption and loss of cerebellar Purkinje cells.

  title={Moderate alcohol consumption and loss of cerebellar Purkinje cells.},
  author={Pekka J. Karhunen and Timo Erkinjuntti and Pekka Laippala},
  volume={308 6945},
OBJECTIVE To examine the dose-response effect of alcohol consumption on the number of cerebellar Purkinje cells. DESIGN A prospective necropsy study combined with detailed reports on use of alcohol from a relative or friend. The number of Purkinje cells was counted in the anterior midsagittal section of the cerebellar vermis, the area of which was measured by computer assisted morphometry. SETTING Department of forensic medicine, University of Helsinki. SUBJECTS 66 men, aged 35 to 69… CONTINUE READING
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