• DOI:10.2174/157016109787354097
Corpus ID: 9268784

Models to study atherosclerosis: a mechanistic insight.

@article{Singh2009ModelsTS,
  title={Models to study atherosclerosis: a mechanistic insight.},
  author={V. Singh and R. Tiwari and M. Dikshit and M. Barthwal},
  journal={Current vascular pharmacology},
  year={2009},
  volume={7 1},
  pages={
          75-109
        }
}

• V. Singh, R. Tiwari, +1 author M. Barthwal
• Published 2009
• Biology, Medicine
• Current vascular pharmacology

The recent failure of candidate drugs like cholesterol ester transfer protein (CETP) and acyl-CoA:cholesterol acyltransferase (ACAT) inhibitors calls for a revised approach for screening anti-atherosclerotic drugs and development of new models of atherosclerosis. For this it is important to understand the mechanism of the disease in a particular model. Models simultaneously showing hyperlipidemia, inflammation and associated complications of diabetes and hypertension will serve the purpose… Expand

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