Models of hemorrhagic shock: differences in the physiological and inflammatory response.

@article{Pfeifer2013ModelsOH,
  title={Models of hemorrhagic shock: differences in the physiological and inflammatory response.},
  author={Roman Pfeifer and Philipp Lichte and Helen Schreiber and Richard Martin Sellei and Thomas Dienstknecht and C Mohammad Sadeghi and H. -Ch. Pape and Philipp Kobbe},
  journal={Cytokine},
  year={2013},
  volume={61 2},
  pages={585-90}
}
INTRODUCTION The hemorrhagic shock (HS) model is commonly used to initiate a systemic post-traumatic inflammatory response. Numerous experimental protocols exist and it is unclear how differences in these models affect the immune response making it difficult to compare results between studies. The aim of this study was to compare the inflammatory response of different established protocols for volume-controlled shock in a murine model. METHODS Male C57/BL6 mice 6-10 weeks and weighing 20-25 g… CONTINUE READING