Models of collective cell spreading with variable cell aspect ratio: a motivation for degenerate diffusion models.

@article{Simpson2011ModelsOC,
  title={Models of collective cell spreading with variable cell aspect ratio: a motivation for degenerate diffusion models.},
  author={Matthew J. Simpson and Ruth E. Baker and Scott W. McCue},
  journal={Physical review. E, Statistical, nonlinear, and soft matter physics},
  year={2011},
  volume={83 2 Pt 1},
  pages={
          021901
        }
}
Continuum diffusion models are often used to represent the collective motion of cell populations. Most previous studies have simply used linear diffusion to represent collective cell spreading, while others found that degenerate nonlinear diffusion provides a better match to experimental cell density profiles. In the cell modeling literature there is no guidance available with regard to which approach is more appropriate for representing the spreading of cell populations. Furthermore, there is… CONTINUE READING

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