Models of coding sequence evolution

@article{Delport2008ModelsOC,
  title={Models of coding sequence evolution},
  author={Wayne Delport and Konrad Scheffler and Cathal Seoighe},
  journal={Briefings in bioinformatics},
  year={2008},
  volume={10 1},
  pages={
          97-109
        }
}
Probabilistic models of sequence evolution are in widespread use in phylogenetics and molecular sequence evolution. These models have become increasingly sophisticated and combined with statistical model comparison techniques have helped to shed light on how genes and proteins evolve. Models of codon evolution have been particularly useful, because, in addition to providing a significant improvement in model realism for protein-coding sequences, codon models can also be designed to test… CONTINUE READING

Similar Papers

Citations

Publications citing this paper.
SHOWING 1-10 OF 41 CITATIONS

Integrating sequence variation and protein structure to identify sites under selection.

  • Molecular biology and evolution
  • 2012
VIEW 7 EXCERPTS
CITES BACKGROUND & METHODS
HIGHLY INFLUENCED

References

Publications referenced by this paper.
SHOWING 1-10 OF 101 REFERENCES

Dependence among sites in RNA evolution.

  • Molecular biology and evolution
  • 2006
VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL

A Bayesian model comparison approach to inferring positive selection.

  • Molecular biology and evolution
  • 2005
VIEW 6 EXCERPTS
HIGHLY INFLUENTIAL

Bayesian Estimation of Positively Selected Sites

  • Journal of Molecular Evolution
  • 2004
VIEW 6 EXCERPTS
HIGHLY INFLUENTIAL