Models of Alzheimer's disease: cellular and molecular aspects.

  title={Models of Alzheimer's disease: cellular and molecular aspects.},
  author={Siegfried Hoyer},
  journal={Journal of neural transmission. Supplementum},
  • Siegfried Hoyer
  • Published 1997 in Journal of neural transmission. Supplementum
Glucose metabolism in the brain is an important process that influences many normal cellular processes, from neurotransmitter synthesis to ATP production. While cortisol and insulin have opposing effects on glucose metabolism, desensitization of the neuronal insulin receptor results in metabolic abnormalities. In the normal aging brain, glucose/energy… CONTINUE READING