Models in Systems Biology: the Parameter Problem and the Meanings of Robustness

  title={Models in Systems Biology: the Parameter Problem and the Meanings of Robustness},
  • Published 2008
I co-teach a graduate course at Harvard called “An Introduction to Systems Biology”. It covers some of the mathematical methods used to build mechanistic models of molecular and cellular systems. Beginning students tend to ask two kinds of questions. Those with a biological background say “Why do I need to use mathematical models? What can they tell me that conventional biological methods cannot?”, while those from the physical sciences (mathematics, physics, engineering) or computer science… CONTINUE READING


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