Models and mechanisms of hyperalgesia and allodynia.

@article{Sandkhler2009ModelsAM,
  title={Models and mechanisms of hyperalgesia and allodynia.},
  author={J{\"u}rgen Sandk{\"u}hler},
  journal={Physiological reviews},
  year={2009},
  volume={89 2},
  pages={
          707-58
        }
}
Hyperalgesia and allodynia are frequent symptoms of disease and may be useful adaptations to protect vulnerable tissues. Both may, however, also emerge as diseases in their own right. Considerable progress has been made in developing clinically relevant animal models for identifying the most significant underlying mechanisms. This review deals with experimental models that are currently used to measure (sect. II) or to induce (sect. III) hyperalgesia and allodynia in animals. Induction and… 
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