Models and algorithms for genome rearrangement with positional constraints

@inproceedings{Swenson2015ModelsAA,
  title={Models and algorithms for genome rearrangement with positional constraints},
  author={Krister M. Swenson and Mathieu Blanchette},
  booktitle={Algorithms for Molecular Biology},
  year={2015}
}
Traditionally, the merit of a rearrangement scenario between two gene orders has been measured based on a parsimony criteria alone; two scenarios with the same number of rearrangements are considered equally good. In this paper, we acknowledge that each rearrangement has a certain likelihood of occurring based on biological constraints, e.g. physical… CONTINUE READING