Models: stretching the skills of cell lines and mice

@article{Marx2014ModelsST,
  title={Models: stretching the skills of cell lines and mice},
  author={V. Marx},
  journal={Nature Methods},
  year={2014},
  volume={11},
  pages={617-620}
}
  • V. Marx
  • Published 2014
  • Medicine, Biology
  • Nature Methods
Cell lines are better. Mice are better. Beyond disagreement about model systems and even passionate discord at times, new strategies help to explore the middle ground so models might better approximate human biology. 
15 Citations
Global Conservation of Protein Status between Cell Lines and Xenografts1
  • 6
  • Highly Influenced
Challenges and opportunities for cell line secretomes in cancer proteomics
  • 15
Fundamental parameters of the developing thymic epithelium in the mouse
  • 9
  • PDF
Novel therapeutic targets on the horizon for lung cancer.
  • 109
Animal models of gastrointestinal and liver diseases. Animal models of cystic fibrosis: gastrointestinal, pancreatic, and hepatobiliary disease and pathophysiology.
  • 39
  • PDF
Nonmulberry Silk Braids Direct Terminal Osteocytic Differentiation through Activation of Wnt-Signaling.
  • 9
  • PDF
Predictive biomarkers of resistance to hypofractionated radiotherapy in high grade glioma
  • 5
...
1
2
...

References

SHOWING 1-5 OF 5 REFERENCES
Genomic responses in mouse models poorly mimic human inflammatory diseases
  • 1,741
  • PDF
Epidermal growth factor receptor mutations in lung adenocarcinoma
  • 173
  • PDF