Modelling transdermal drug delivery using microneedles: effect of geometry on drug transport behaviour.

@article{Olatunji2012ModellingTD,
  title={Modelling transdermal drug delivery using microneedles: effect of geometry on drug transport behaviour.},
  author={Ololade Olatunji and Diganta Bhusan Das and V. Nassehi},
  journal={Journal of pharmaceutical sciences},
  year={2012},
  volume={101 1},
  pages={164-75}
}
Transdermal drug delivery using microneedles (MNs) depends on the rate of drug transport through the viable epidermis. Therefore, minimising the distance between the drug-loaded surface and the microcirculation in the dermis where the drug is absorbed into the body is significant in improving drug delivery efficiency. A quantifiable relationship between MN design parameters and skin diffusion properties is therefore desirable, which is what this study aims to achieve. A framework is presented… CONTINUE READING