Modelling the widespread effects of TOC1 signalling on the plant circadian clock and its outputs

@inproceedings{Pokhilko2012ModellingTW,
  title={Modelling the widespread effects of TOC1 signalling on the plant circadian clock and its outputs},
  author={Alexandra V. Pokhilko and Paloma Mas and Andrew J. Millar},
  booktitle={BMC Systems Biology},
  year={2012}
}
24-hour biological clocks are intimately connected to the cellular signalling network, which complicates the analysis of clock mechanisms. The transcriptional regulator TOC1 (TIMING OF CAB EXPRESSION 1) is a founding component of the gene circuit in the plant circadian clock. Recent results show that TOC1 suppresses transcription of multiple target genes within the clock circuit, far beyond its previously-described regulation of the morning transcription factors LHY (LATE ELONGATED HYPOCOTYL… CONTINUE READING
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