Modelling the role of catastrophe, crossover and Katanin in the self organisation of cortical microtubules

@inproceedings{Mace2015ModellingTR,
  title={Modelling the role of catastrophe, crossover and Katanin in the self organisation of cortical microtubules},
  author={Alex Mace and Wenjia Wang},
  year={2015}
}
Cortical microtubules can form ordered arrays through interactions among themselves. When an incident microtubule collides with a barrier microtubule it may entrain if below a certain angle of collision. Else it undergoes collision induced catastrophe (CIC) or crosses over the barrier microtubule. It has been proposed that katanin, a microtubule severing protein, contributes to ordering by severing the overlying microtubule at these crossover sites. We present a 3-state computational model to… CONTINUE READING