Modelling the effect of myosin X motors on filopodia growth.

  title={Modelling the effect of myosin X motors on filopodia growth.},
  author={K Wolff and C Barrett-Freeman and Martin R. Evans and Andrew B. Goryachev and Davide Marenduzzo},
  journal={Physical biology},
  volume={11 1},
We present a numerical simulation study of the dynamics of filopodial growth in the presence of active transport by myosin X motors. We employ both a microscopic agent-based model, which captures the stochasticity of the growth process, and a continuum mean-field theory which neglects fluctuations. We show that in the absence of motors, filopodia growth is overestimated by the continuum mean-field theory. Thus fluctuations slow down the growth, especially when the protrusions are driven by a… 

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