Modelling the cost-effectiveness of strategies to prevent tuberculosis in child contacts in a high-burden setting.

@article{Mandalakas2013ModellingTC,
  title={Modelling the cost-effectiveness of strategies to prevent tuberculosis in child contacts in a high-burden setting.},
  author={Anna Maria Mandalakas and Anneke Catharina Hesseling and Robert Gie and Hendrick Simon Schaaf and Ben J. Marais and Edina Sinanovic},
  journal={Thorax},
  year={2013},
  volume={68 3},
  pages={247-55}
}
BACKGROUND WHO recommends isoniazid preventive therapy (IPT) for young children in close contact with an infectious tuberculosis (TB) case. No models have examined the cost effectiveness of this recommendation. METHODS A decision analysis model was developed to estimate health and economic outcomes of five TB infection screening strategies in young household contacts. In the no-testing strategy, children received IPT based on age and reported exposure. Other strategies included testing for… CONTINUE READING
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