Modelling of the relationship between cell dimensions and mean electron dose delivered to the cell nucleus: application to five radionuclides used in nuclear medicine.

@article{Gardin1995ModellingOT,
  title={Modelling of the relationship between cell dimensions and mean electron dose delivered to the cell nucleus: application to five radionuclides used in nuclear medicine.},
  author={Isabelle Gardin and Moshe Faraggi and E Huc and Bernard D. Bok},
  journal={Physics in medicine and biology},
  year={1995},
  volume={40 6},
  pages={1001-14}
}
The mean dose delivered to the cell nucleus by electron emissions of 99Tcm, 123I, 111In, 67Ga and 201Tl was evaluated at the subcellular level. Models were applied assuming uniform distributions of radioactivity throughout the nucleus, the cytoplasm or the cell membrane, allowing computation of the total absorbed fraction, phi and S-values to the cell nucleus as a function of cell dimensions. The graphs of phi plotted according to cell dimensions show that the dose to the cell nucleus strongly… CONTINUE READING