Modelling of spray-freezing with compressed carbon dioxide

  title={Modelling of spray-freezing with compressed carbon dioxide},
  author={Marek Henczka and Jerzy Bałdyga and Boris Yu. Shekunov},
Abstract A spray-freezing process with compressed carbon dioxide is investigated. The objective of the study is related to production of composite powders of water-soluble bioactive molecules and stabilizing excipients with specific aim to obtain stable protein particles with a narrow size distribution for pharmaceutical purposes. A model of dispersion and solidification of aqueous droplets in turbulent flow field in the spray-freezing process based on expansion of compressed carbon dioxide is… CONTINUE READING