Modelling of chemotherapy: The effective dose approach

  title={Modelling of chemotherapy: The effective dose approach},
  author={Dirk Hasenclever and Oana Brosteanu and Torsten G. Gerike and Markus L{\"o}ffler},
  journal={Annals of Hematology},
We sketch the development of the effective dose approach which provides a theoretical framework to interpret chemotherapy outcome data. Building on the generalised Skipper model of chemotherapy, a meta-regression method is derived to jointly analyse all chemotherapy comparing randomised clinical trials in a given malignancy in order to explore the slope of… CONTINUE READING