Modelling intrinsic electrophysiological properties of ON and OFF retinal ganglion cells

@article{Kameneva2011ModellingIE,
  title={Modelling intrinsic electrophysiological properties of ON and OFF retinal ganglion cells},
  author={Tatiana Kameneva and Hamish Meffin and Anthony N. Burkitt},
  journal={Journal of Computational Neuroscience},
  year={2011},
  volume={31},
  pages={547-561}
}
ON and OFF retinal ganglion cells (RGCs) display differences in their intrinsic electrophysiology: OFF cells maintain spontaneous activity in the absence of any input, exhibit subthreshold membrane potential oscillations, rebound excitation and burst firing; ON cells require excitatory input to drive their activity and display none of the aforementioned phenomena. The goal of this study was to identify and characterize ionic currents that explain these intrinsic electrophysiological differences… CONTINUE READING

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