Modelling heterotachy in phylogenetic inference by reversible-jump Markov chain Monte Carlo.

@article{Pagel2008ModellingHI,
  title={Modelling heterotachy in phylogenetic inference by reversible-jump Markov chain Monte Carlo.},
  author={Mark Pagel and Andrew Meade},
  journal={Philosophical transactions of the Royal Society of London. Series B, Biological sciences},
  year={2008},
  volume={363 1512},
  pages={3955-64}
}
The rate at which a given site in a gene sequence alignment evolves over time may vary. This phenomenon--known as heterotachy--can bias or distort phylogenetic trees inferred from models of sequence evolution that assume rates of evolution are constant. Here, we describe a phylogenetic mixture model designed to accommodate heterotachy. The method sums the likelihood of the data at each site over more than one set of branch lengths on the same tree topology. A branch-length set that is best for… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 34 extracted citations

Recent trends in molecular phylogenetic analysis: where to next?

The Journal of heredity • 2011
View 4 Excerpts
Highly Influenced

References

Publications referenced by this paper.
Showing 1-10 of 48 references

A phylogenetic mixture model for heterotachy

A. Meade, M. Pagel
Evolutionary biology from concept to application • 2008
View 14 Excerpts
Highly Influenced

Bayesian Data Analysis for Data Mining

2002
View 4 Excerpts
Highly Influenced

Phylogeny of the Chlorophyceae with special reference to the Sphaeropleales: a study of 18S and 26S rDNA data

M. A. Buchheim, E. A. Michalopulos, J. A. Buchheim
J. Phycol • 2001
View 4 Excerpts
Highly Influenced

Introducing Markov chain Monte Carlo. In Markov chain Monte Carlo in practice (eds

W. R. Gilks, S. Richardson, D. J. Spiegelhalter
1996
View 4 Excerpts
Highly Influenced

Phylogeny reconstruction

D. L. Swofford, G. J. Olsen, +3 authors B. K. Mable
In Molecular Systematics, • 1996
View 4 Excerpts
Highly Influenced

A mixed branch length model of heterotachy improves phylogenetic accuracy.

Molecular biology and evolution • 2008
View 3 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…