Modelling for Computer Controlled Neuromuscular Blockade

  title={Modelling for Computer Controlled Neuromuscular Blockade},
  author={T. J. Gilhuly and Guy A. Dumont and B. A. MacLeod},
  journal={2005 IEEE Engineering in Medicine and Biology 27th Annual Conference},
In this paper we present data collection and methods for the selection of a model class with the goal of automated neuromuscular blockade (NMB). Neuromuscular response was measured in the presence of rocuronium in rabbits (N=S) and humans (N=14). An average response was formed and used to determine optimal ARX and Laguerre representations for a wide range of orders and parameters. A 6th order Laguerre model was selected based on its accuracy and simplicity. Models were identified for each… CONTINUE READING

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